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The third patient experienced stable disease and improved well-being even though chemotherapy had been deemed highly unlikely to be beneficial (patient 13).
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Treatment morbidity associated with the management of the axilla in breast-conserving therapy.
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The benefits of fluorouracil-based adjuvant chemotherapy in reducing the risk of relapse and prolonging survival in patients with resected colon cancer are well established, particularly in stage III disease.
These results demonstrated that the EGFR high expression (in both mRNA and protein level) is correlated to the response to cetuximab.
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Most of these people will have passed away by the end of the first year.
Dudley ME, Wunderlich JR, Yang JC, Sherry RM, Topalian SL, Restifo NP, Royal RE, Kammula U, White DE, Mavroukakis SA, Rogers LJ, Gracia GJ, Jones SA, Mangiameli DP, Pelletier MM, Gea-Banacloche J, Robinson MR, Berman DM, Filie AC, Abati A, Rosenberg SA (2005) Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma.
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Three patients (patients 10, 11, 13) had unusually favorable experiences that were deemed highly unlikely to result from chemotherapy alone (probability much less than 33%).
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CAPIRI-Bev has a less favourable toxicity profile, requiring dose reductions, in order to be considered as an option in first-line treatment of patients with mCRC.
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In addition, the AUC of in tumor via capecitabine dosing was 18- to 32-fold higher than via direct 5-FU dosing, demonstrating that capecitabine is efficiently converted to 5-FU in the tumors.
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As reported by Vasen et al in the Journal of Clinical Oncology, surveillance for pancreatic ductal adenocarcinoma in high-risk individuals appears to be of benefit in individuals at risk due to CDKN2A mutation, with the advantage being less clear among individuals at risk due to familial clustering of pancreatic cancer.
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Use of Cytotoxic Chemotherapy in Metastatic Breast Cancer: Putting Taxanes in Perspective.
The Impact of Drug Vintage on Patient Survival: A Patient-Level Analysis Using Quebec's Provincial Health Plan Data.
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Biomarker evaluation in the phase III, placebo (P)-controlled, randomized BeTa trial of bevacizumab (B) and erlotinib (E) for patients (Pts) with advanced non-small cell lung cancer (NSCLC) after failure of standard 1st line chemotherapy: correlation with treatment outcomes.
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Hoff P, Tabernero J, Shen L, Ohtsu A, Yu R, Szado T, Kang Y (2013) Pertuzumab, trastuzumab and chemotherapy in HER2-positive metastatic gastric or gastro-oesophageal junction cancer: an international phase III study (JACOB).
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